Captopril vs Omeprazole

Captopril vs Omeprazole: Overview

This comparison examines the pharmacological differences between Captopril and Omeprazole.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Omeprazole: Proton pump inhibitor that irreversibly blocks H+/K+-ATPase.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Omeprazole — 0.5-1 hour.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Omeprazole — C17H19N3O3S.

Molecular Weight: Captopril — 217.2850 g/mol; Omeprazole — 345.4170 g/mol.

Type: Captopril — Small molecule; Omeprazole — Small molecule.