Captopril vs Phenytoin

Captopril vs Phenytoin: Overview

This comparison examines the pharmacological differences between Captopril and Phenytoin.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Phenytoin: Sodium channel blocker stabilizing inactive state.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Phenytoin — 22 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Phenytoin — C15H12N2O2.

Molecular Weight: Captopril — 217.2850 g/mol; Phenytoin — 252.2680 g/mol.

Type: Captopril — Small molecule; Phenytoin — Small molecule.