Captopril vs Pravastatin

Captopril vs Pravastatin: Overview

This comparison examines the pharmacological differences between Captopril and Pravastatin.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Pravastatin: Competitive inhibitor of HMG-CoA reductase.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Pravastatin — 1.8 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Pravastatin — C23H36O7.

Molecular Weight: Captopril — 217.2850 g/mol; Pravastatin — 424.5280 g/mol.

Type: Captopril — Small molecule; Pravastatin — Small molecule.