Celecoxib vs Erlotinib

## Celecoxib vs Erlotinib: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Erlotinib**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Erlotinib**: Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Erlotinib — 36 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Erlotinib — C22H23N3O4.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Erlotinib — 393.4380 g/mol.

**Type**: Celecoxib — Small molecule; Erlotinib — Small molecule.