Celecoxib vs Hydrochlorothiazide

Celecoxib vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between Celecoxib and Hydrochlorothiazide.

Mechanism of Action

Celecoxib: Selective COX-2 inhibitor.

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Pharmacokinetics

Half-life: Celecoxib — 11 hours; Hydrochlorothiazide — 6-15 hours.

Chemical Properties

Molecular Formula: Celecoxib — C17H14F3N3O2S; Hydrochlorothiazide — C7H8ClN3O4S2.

Molecular Weight: Celecoxib — 381.3730 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

Type: Celecoxib — Small molecule; Hydrochlorothiazide — Small molecule.