Celecoxib vs Hydrochlorothiazide

## Celecoxib vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Hydrochlorothiazide**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Celecoxib — Small molecule; Hydrochlorothiazide — Small molecule.