Celecoxib vs Ibuprofen

Celecoxib vs Ibuprofen: Overview

This comparison examines the pharmacological differences between Celecoxib and Ibuprofen.

Mechanism of Action

Celecoxib: Selective COX-2 inhibitor.

Ibuprofen: Non-selective COX inhibitor reducing prostaglandin synthesis.

Pharmacokinetics

Half-life: Celecoxib — 11 hours; Ibuprofen — 2-4 hours.

Chemical Properties

Molecular Formula: Celecoxib — C17H14F3N3O2S; Ibuprofen — C13H18O2.

Molecular Weight: Celecoxib — 381.3730 g/mol; Ibuprofen — 206.2810 g/mol.

Type: Celecoxib — Small molecule; Ibuprofen — Small molecule.