Celecoxib vs Trimethoprim

## Celecoxib vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Trimethoprim**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Celecoxib — Small molecule; Trimethoprim — Small molecule.