Cephalexin vs Clindamycin

Cephalexin vs Clindamycin: Overview

This comparison examines the pharmacological differences between Cephalexin and Clindamycin.

Mechanism of Action

Cephalexin: First-generation cephalosporin inhibiting cell wall synthesis.

Clindamycin: Binds 50S ribosomal subunit inhibiting protein synthesis.

Pharmacokinetics

Half-life: Cephalexin — 0.5-1.2 hours; Clindamycin — 2-3 hours.

Chemical Properties

Molecular Formula: Cephalexin — C16H17N3O4S; Clindamycin — C18H33ClN2O5S.

Molecular Weight: Cephalexin — 347.3890 g/mol; Clindamycin — 424.9830 g/mol.

Type: Cephalexin — Small molecule; Clindamycin — Small molecule.