Ciprofloxacin vs Fluconazole

Ciprofloxacin vs Fluconazole: Overview

This comparison examines the pharmacological differences between Ciprofloxacin and Fluconazole.

Mechanism of Action

Ciprofloxacin: Inhibits bacterial DNA gyrase and topoisomerase IV.

Fluconazole: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

Pharmacokinetics

Half-life: Ciprofloxacin — 4 hours; Fluconazole — 30 hours.

Chemical Properties

Molecular Formula: Ciprofloxacin — C17H18FN3O3; Fluconazole — C13H12F2N6O.

Molecular Weight: Ciprofloxacin — 331.3460 g/mol; Fluconazole — 306.2710 g/mol.

Type: Ciprofloxacin — Small molecule; Fluconazole — Small molecule.