Ciprofloxacin vs Metronidazole

Ciprofloxacin vs Metronidazole: Overview

This comparison examines the pharmacological differences between Ciprofloxacin and Metronidazole.

Mechanism of Action

Ciprofloxacin: Inhibits bacterial DNA gyrase and topoisomerase IV.

Metronidazole: Forms cytotoxic free radicals that damage bacterial DNA.

Pharmacokinetics

Half-life: Ciprofloxacin — 4 hours; Metronidazole — 8 hours.

Chemical Properties

Molecular Formula: Ciprofloxacin — C17H18FN3O3; Metronidazole — C6H9N3O3.

Molecular Weight: Ciprofloxacin — 331.3460 g/mol; Metronidazole — 171.1540 g/mol.

Type: Ciprofloxacin — Small molecule; Metronidazole — Small molecule.