Ciprofloxacin vs Vancomycin

Ciprofloxacin vs Vancomycin: Overview

This comparison examines the pharmacological differences between Ciprofloxacin and Vancomycin.

Mechanism of Action

Ciprofloxacin: Inhibits bacterial DNA gyrase and topoisomerase IV.

Vancomycin: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

Pharmacokinetics

Half-life: Ciprofloxacin — 4 hours; Vancomycin — 4-6 hours.

Chemical Properties

Molecular Formula: Ciprofloxacin — C17H18FN3O3; Vancomycin — C66H75Cl2N9O24.

Molecular Weight: Ciprofloxacin — 331.3460 g/mol; Vancomycin — 1449.2500 g/mol.

Type: Ciprofloxacin — Small molecule; Vancomycin — Small molecule.