Citalopram vs Fluoxetine

Citalopram vs Fluoxetine: Overview

This comparison examines the pharmacological differences between Citalopram and Fluoxetine.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Fluoxetine: Selective serotonin reuptake inhibitor (SSRI).

Pharmacokinetics

Half-life: Citalopram — 35 hours; Fluoxetine — 1-3 days.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Fluoxetine — C17H18F3NO.

Molecular Weight: Citalopram — 324.3920 g/mol; Fluoxetine — 309.3260 g/mol.

Type: Citalopram — Small molecule; Fluoxetine — Small molecule.