Citalopram vs Hydrochlorothiazide

Citalopram vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between Citalopram and Hydrochlorothiazide.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Hydrochlorothiazide — 6-15 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Hydrochlorothiazide — C7H8ClN3O4S2.

Molecular Weight: Citalopram — 324.3920 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

Type: Citalopram — Small molecule; Hydrochlorothiazide — Small molecule.