Citalopram vs Lorazepam

Citalopram vs Lorazepam: Overview

This comparison examines the pharmacological differences between Citalopram and Lorazepam.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Lorazepam: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Lorazepam — 10-20 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Lorazepam — C15H10Cl2N2O2.

Molecular Weight: Citalopram — 324.3920 g/mol; Lorazepam — 321.1580 g/mol.

Type: Citalopram — Small molecule; Lorazepam — Small molecule.