Citalopram vs Methotrexate

Citalopram vs Methotrexate: Overview

This comparison examines the pharmacological differences between Citalopram and Methotrexate.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Methotrexate: Dihydrofolate reductase inhibitor.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Methotrexate — 3-10 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Methotrexate — C20H22N8O5.

Molecular Weight: Citalopram — 324.3920 g/mol; Methotrexate — 454.4400 g/mol.

Type: Citalopram — Small molecule; Methotrexate — Small molecule.