Citalopram vs Sildenafil

Citalopram vs Sildenafil: Overview

This comparison examines the pharmacological differences between Citalopram and Sildenafil.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Sildenafil: Selective PDE5 inhibitor increasing cGMP.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Sildenafil — 4 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Sildenafil — C22H30N6O4S.

Molecular Weight: Citalopram — 324.3920 g/mol; Sildenafil — 474.5800 g/mol.

Type: Citalopram — Small molecule; Sildenafil — Small molecule.