Citalopram vs Sitagliptin

Citalopram vs Sitagliptin: Overview

This comparison examines the pharmacological differences between Citalopram and Sitagliptin.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Sitagliptin: DPP-4 inhibitor increasing incretin levels.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Sitagliptin — 12.4 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Sitagliptin — C16H15F6N5O.

Molecular Weight: Citalopram — 324.3920 g/mol; Sitagliptin — 407.3140 g/mol.

Type: Citalopram — Small molecule; Sitagliptin — Small molecule.