Citalopram vs Tofacitinib

Citalopram vs Tofacitinib: Overview

This comparison examines the pharmacological differences between Citalopram and Tofacitinib.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Tofacitinib: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

Pharmacokinetics

Half-life: Citalopram — 35 hours; Tofacitinib — 3.2 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Tofacitinib — C16H20N6O.

Molecular Weight: Citalopram — 324.3920 g/mol; Tofacitinib — 312.3700 g/mol.

Type: Citalopram — Small molecule; Tofacitinib — Small molecule.