Citalopram vs Venlafaxine

Citalopram vs Venlafaxine: Overview

This comparison examines the pharmacological differences between Citalopram and Venlafaxine.

Mechanism of Action

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Venlafaxine: Serotonin-norepinephrine reuptake inhibitor (SNRI).

Pharmacokinetics

Half-life: Citalopram — 35 hours; Venlafaxine — 5 hours.

Chemical Properties

Molecular Formula: Citalopram — C20H21FN2O; Venlafaxine — C17H27NO2.

Molecular Weight: Citalopram — 324.3920 g/mol; Venlafaxine — 277.4020 g/mol.

Type: Citalopram — Small molecule; Venlafaxine — Small molecule.