Cyclosporine vs Fluconazole

Cyclosporine vs Fluconazole: Overview

This comparison examines the pharmacological differences between Cyclosporine and Fluconazole.

Mechanism of Action

Cyclosporine: Calcineurin inhibitor suppressing T-cell activation.

Fluconazole: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

Pharmacokinetics

Half-life: Cyclosporine — 6-12 hours; Fluconazole — 30 hours.

Chemical Properties

Molecular Formula: Cyclosporine — C62H111N11O12; Fluconazole — C13H12F2N6O.

Molecular Weight: Cyclosporine — 1202.6100 g/mol; Fluconazole — 306.2710 g/mol.

Type: Cyclosporine — Protein; Fluconazole — Small molecule.