Cyclosporine vs Hydrochlorothiazide

Cyclosporine vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between Cyclosporine and Hydrochlorothiazide.

Mechanism of Action

Cyclosporine: Calcineurin inhibitor suppressing T-cell activation.

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Pharmacokinetics

Half-life: Cyclosporine — 6-12 hours; Hydrochlorothiazide — 6-15 hours.

Chemical Properties

Molecular Formula: Cyclosporine — C62H111N11O12; Hydrochlorothiazide — C7H8ClN3O4S2.

Molecular Weight: Cyclosporine — 1202.6100 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

Type: Cyclosporine — Protein; Hydrochlorothiazide — Small molecule.