Cyclosporine vs Methylprednisolone

Cyclosporine vs Methylprednisolone: Overview

This comparison examines the pharmacological differences between Cyclosporine and Methylprednisolone.

Mechanism of Action

Cyclosporine: Calcineurin inhibitor suppressing T-cell activation.

Methylprednisolone: Intermediate-acting synthetic glucocorticoid.

Pharmacokinetics

Half-life: Cyclosporine — 6-12 hours; Methylprednisolone — 18-36 hours.

Chemical Properties

Molecular Formula: Cyclosporine — C62H111N11O12; Methylprednisolone — C22H30O5.

Molecular Weight: Cyclosporine — 1202.6100 g/mol; Methylprednisolone — 374.4710 g/mol.

Type: Cyclosporine — Protein; Methylprednisolone — Small molecule.