Dexamethasone vs Methylprednisolone

Dexamethasone vs Methylprednisolone: Overview

This comparison examines the pharmacological differences between Dexamethasone and Methylprednisolone.

Mechanism of Action

Dexamethasone: Potent synthetic glucocorticoid.

Methylprednisolone: Intermediate-acting synthetic glucocorticoid.

Pharmacokinetics

Half-life: Dexamethasone — 36-54 hours; Methylprednisolone — 18-36 hours.

Chemical Properties

Molecular Formula: Dexamethasone — C22H29FO5; Methylprednisolone — C22H30O5.

Molecular Weight: Dexamethasone — 392.4610 g/mol; Methylprednisolone — 374.4710 g/mol.

Type: Dexamethasone — Small molecule; Methylprednisolone — Small molecule.