Dexamethasone vs Prednisone

Dexamethasone vs Prednisone: Overview

This comparison examines the pharmacological differences between Dexamethasone and Prednisone.

Mechanism of Action

Dexamethasone: Potent synthetic glucocorticoid.

Prednisone: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

Pharmacokinetics

Half-life: Dexamethasone — 36-54 hours; Prednisone — 2-3 hours.

Chemical Properties

Molecular Formula: Dexamethasone — C22H29FO5; Prednisone — C21H26O5.

Molecular Weight: Dexamethasone — 392.4610 g/mol; Prednisone — 358.4280 g/mol.

Type: Dexamethasone — Small molecule; Prednisone — Small molecule.