Diazepam vs Phenytoin

Diazepam vs Phenytoin: Overview

This comparison examines the pharmacological differences between Diazepam and Phenytoin.

Mechanism of Action

Diazepam: Positive allosteric modulator of GABA-A receptors.

Phenytoin: Sodium channel blocker stabilizing inactive state.

Pharmacokinetics

Half-life: Diazepam — 20-100 hours; Phenytoin — 22 hours.

Chemical Properties

Molecular Formula: Diazepam — C16H13ClN2O; Phenytoin — C15H12N2O2.

Molecular Weight: Diazepam — 284.7400 g/mol; Phenytoin — 252.2680 g/mol.

Type: Diazepam — Small molecule; Phenytoin — Small molecule.