Digoxin vs Fluconazole

Digoxin vs Fluconazole: Overview

This comparison examines the pharmacological differences between Digoxin and Fluconazole.

Mechanism of Action

Digoxin: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

Fluconazole: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

Pharmacokinetics

Half-life: Digoxin — 36-48 hours; Fluconazole — 30 hours.

Chemical Properties

Molecular Formula: Digoxin — C41H64O14; Fluconazole — C13H12F2N6O.

Molecular Weight: Digoxin — 780.9430 g/mol; Fluconazole — 306.2710 g/mol.

Type: Digoxin — Small molecule; Fluconazole — Small molecule.