Digoxin vs Furosemide

Digoxin vs Furosemide: Overview

This comparison examines the pharmacological differences between Digoxin and Furosemide.

Mechanism of Action

Digoxin: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

Furosemide: Loop diuretic inhibiting Na-K-2Cl cotransporter.

Pharmacokinetics

Half-life: Digoxin — 36-48 hours; Furosemide — 2 hours.

Chemical Properties

Molecular Formula: Digoxin — C41H64O14; Furosemide — C12H11ClN2O5S.

Molecular Weight: Digoxin — 780.9430 g/mol; Furosemide — 330.7440 g/mol.

Type: Digoxin — Small molecule; Furosemide — Small molecule.