Digoxin vs Hydromorphone

Digoxin vs Hydromorphone: Overview

This comparison examines the pharmacological differences between Digoxin and Hydromorphone.

Mechanism of Action

Digoxin: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

Hydromorphone: Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

Pharmacokinetics

Half-life: Digoxin — 36-48 hours; Hydromorphone — 2-3 hours.

Chemical Properties

Molecular Formula: Digoxin — C41H64O14; Hydromorphone — C17H19NO3.

Molecular Weight: Digoxin — 780.9430 g/mol; Hydromorphone — 285.3380 g/mol.

Type: Digoxin — Small molecule; Hydromorphone — Small molecule.