Digoxin vs Trimethoprim

Digoxin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between Digoxin and Trimethoprim.

Mechanism of Action

Digoxin: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

Trimethoprim: Dihydrofolate reductase inhibitor (bacterial selective).

Pharmacokinetics

Half-life: Digoxin — 36-48 hours; Trimethoprim — 8-10 hours.

Chemical Properties

Molecular Formula: Digoxin — C41H64O14; Trimethoprim — C14H18N4O3.

Molecular Weight: Digoxin — 780.9430 g/mol; Trimethoprim — 290.3180 g/mol.

Type: Digoxin — Small molecule; Trimethoprim — Small molecule.