Diphenhydramine vs Fluoxetine

## Diphenhydramine vs Fluoxetine: Overview

This comparison examines the pharmacological differences between **Diphenhydramine** and **Fluoxetine**.

## Mechanism of Action

**Diphenhydramine**: First-generation H1 antihistamine with anticholinergic properties.

**Fluoxetine**: Selective serotonin reuptake inhibitor (SSRI).

## Pharmacokinetics

**Half-life**: Diphenhydramine — 2-8 hours; Fluoxetine — 1-3 days.

## Chemical Properties

**Molecular Formula**: Diphenhydramine — C17H21NO; Fluoxetine — C17H18F3NO.

**Molecular Weight**: Diphenhydramine — 255.3550 g/mol; Fluoxetine — 309.3260 g/mol.

**Type**: Diphenhydramine — Small molecule; Fluoxetine — Small molecule.