Doxycycline vs Metronidazole

Doxycycline vs Metronidazole: Overview

This comparison examines the pharmacological differences between Doxycycline and Metronidazole.

Mechanism of Action

Doxycycline: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

Metronidazole: Forms cytotoxic free radicals that damage bacterial DNA.

Pharmacokinetics

Half-life: Doxycycline — 18-22 hours; Metronidazole — 8 hours.

Chemical Properties

Molecular Formula: Doxycycline — C22H24N2O8; Metronidazole — C6H9N3O3.

Molecular Weight: Doxycycline — 444.4350 g/mol; Metronidazole — 171.1540 g/mol.

Type: Doxycycline — Small molecule; Metronidazole — Small molecule.