Doxycycline vs Norfloxacin

Doxycycline vs Norfloxacin: Overview

This comparison examines the pharmacological differences between Doxycycline and Norfloxacin.

Mechanism of Action

Doxycycline: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

Norfloxacin: Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

Pharmacokinetics

Half-life: Doxycycline — 18-22 hours; Norfloxacin — 3-4 hours.

Chemical Properties

Molecular Formula: Doxycycline — C22H24N2O8; Norfloxacin — C16H18FN3O3.

Molecular Weight: Doxycycline — 444.4350 g/mol; Norfloxacin — 319.3310 g/mol.

Type: Doxycycline — Small molecule; Norfloxacin — Small molecule.