Duloxetine vs Escitalopram

Duloxetine vs Escitalopram: Overview

This comparison examines the pharmacological differences between Duloxetine and Escitalopram.

Mechanism of Action

Duloxetine: Serotonin-norepinephrine reuptake inhibitor (SNRI).

Escitalopram: S-enantiomer of citalopram; selective serotonin reuptake inhibitor.

Pharmacokinetics

Half-life: Duloxetine — 12 hours; Escitalopram — 27-32 hours.

Chemical Properties

Molecular Formula: Duloxetine — C18H19NOS; Escitalopram — C20H21FN2O.

Molecular Weight: Duloxetine — 297.4150 g/mol; Escitalopram — 324.3920 g/mol.

Type: Duloxetine — Small molecule; Escitalopram — Small molecule.