Duloxetine vs Trazodone

Duloxetine vs Trazodone: Overview

This comparison examines the pharmacological differences between Duloxetine and Trazodone.

Mechanism of Action

Duloxetine: Serotonin-norepinephrine reuptake inhibitor (SNRI).

Trazodone: Serotonin antagonist and reuptake inhibitor (SARI).

Pharmacokinetics

Half-life: Duloxetine — 12 hours; Trazodone — 5-9 hours.

Chemical Properties

Molecular Formula: Duloxetine — C18H19NOS; Trazodone — C19H22ClN5O.

Molecular Weight: Duloxetine — 297.4150 g/mol; Trazodone — 371.8640 g/mol.

Type: Duloxetine — Small molecule; Trazodone — Small molecule.