Durvalumab vs Loratadine

## Durvalumab vs Loratadine: Overview

This comparison examines the pharmacological differences between **Durvalumab** and **Loratadine**.

## Mechanism of Action

**Durvalumab**: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

## Pharmacokinetics

**Half-life**: Durvalumab — 17 days; Loratadine — 8 hours.

## Chemical Properties

**Molecular Formula**: Durvalumab — N/A; Loratadine — C22H23ClN2O2.

**Molecular Weight**: Durvalumab — N/A; Loratadine — 382.8800 g/mol.

**Type**: Durvalumab — Antibody; Loratadine — Small molecule.