Durvalumab vs Sertraline

Durvalumab vs Sertraline: Overview

This comparison examines the pharmacological differences between Durvalumab and Sertraline.

Mechanism of Action

Durvalumab: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

Sertraline: Selective serotonin reuptake inhibitor (SSRI).

Pharmacokinetics

Half-life: Durvalumab — 17 days; Sertraline — 26 hours.

Chemical Properties

Molecular Formula: Sertraline — C17H17Cl2N.

Molecular Weight: Sertraline — 306.2290 g/mol.

Type: Durvalumab — Antibody; Sertraline — Small molecule.