Durvalumab vs Vancomycin

Durvalumab vs Vancomycin: Overview

This comparison examines the pharmacological differences between Durvalumab and Vancomycin.

Mechanism of Action

Durvalumab: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

Vancomycin: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

Pharmacokinetics

Half-life: Durvalumab — 17 days; Vancomycin — 4-6 hours.

Chemical Properties

Molecular Formula: Vancomycin — C66H75Cl2N9O24.

Molecular Weight: Vancomycin — 1449.2500 g/mol.

Type: Durvalumab — Antibody; Vancomycin — Small molecule.