Empagliflozin vs Metformin

Empagliflozin vs Metformin: Overview

This comparison examines the pharmacological differences between Empagliflozin and Metformin.

Mechanism of Action

Empagliflozin: Selective SGLT2 inhibitor reducing renal glucose reabsorption.

Metformin: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

Pharmacokinetics

Half-life: Empagliflozin — 12.4 hours; Metformin — 4-9 hours.

Chemical Properties

Molecular Formula: Empagliflozin — C23H27ClO7; Metformin — C4H11N5.

Molecular Weight: Empagliflozin — 450.9100 g/mol; Metformin — 129.1640 g/mol.

Type: Empagliflozin — Small molecule; Metformin — Small molecule.