Enalapril vs Simvastatin

Enalapril vs Simvastatin: Overview

This comparison examines the pharmacological differences between Enalapril and Simvastatin.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Simvastatin: Prodrug converted to active form that inhibits HMG-CoA reductase.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Simvastatin — 2 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Simvastatin — C25H38O5.

Molecular Weight: Enalapril — 376.4470 g/mol; Simvastatin — 418.5700 g/mol.

Type: Enalapril — Small molecule; Simvastatin — Small molecule.