Enalapril vs Sitagliptin

Enalapril vs Sitagliptin: Overview

This comparison examines the pharmacological differences between Enalapril and Sitagliptin.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Sitagliptin: DPP-4 inhibitor increasing incretin levels.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Sitagliptin — 12.4 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Sitagliptin — C16H15F6N5O.

Molecular Weight: Enalapril — 376.4470 g/mol; Sitagliptin — 407.3140 g/mol.

Type: Enalapril — Small molecule; Sitagliptin — Small molecule.