Enalapril vs Spironolactone

Enalapril vs Spironolactone: Overview

This comparison examines the pharmacological differences between Enalapril and Spironolactone.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Spironolactone: Mineralocorticoid receptor antagonist.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Spironolactone — 1.4 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Spironolactone — C24H32O4S.

Molecular Weight: Enalapril — 376.4470 g/mol; Spironolactone — 416.5740 g/mol.

Type: Enalapril — Small molecule; Spironolactone — Small molecule.