Enalapril vs Telmisartan

Enalapril vs Telmisartan: Overview

This comparison examines the pharmacological differences between Enalapril and Telmisartan.

Mechanism of Action

Enalapril: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Telmisartan: Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

Pharmacokinetics

Half-life: Enalapril — 11 hours; Telmisartan — 24 hours.

Chemical Properties

Molecular Formula: Enalapril — C20H28N2O5; Telmisartan — C33H30N4O2.

Molecular Weight: Enalapril — 376.4470 g/mol; Telmisartan — 514.6230 g/mol.

Type: Enalapril — Small molecule; Telmisartan — Small molecule.