Fentanyl vs Gabapentin

Fentanyl vs Gabapentin: Overview

This comparison examines the pharmacological differences between Fentanyl and Gabapentin.

Mechanism of Action

Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Gabapentin: Binds alpha-2-delta subunit of voltage-gated calcium channels.

Pharmacokinetics

Half-life: Fentanyl — 2-4 hours; Gabapentin — 5-7 hours.

Chemical Properties

Molecular Formula: Fentanyl — C22H28N2O; Gabapentin — C9H17NO2.

Molecular Weight: Fentanyl — 336.4700 g/mol; Gabapentin — 171.2370 g/mol.

Type: Fentanyl — Small molecule; Gabapentin — Small molecule.