Fentanyl vs Sildenafil

Fentanyl vs Sildenafil: Overview

This comparison examines the pharmacological differences between Fentanyl and Sildenafil.

Mechanism of Action

Fentanyl: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Sildenafil: Selective PDE5 inhibitor increasing cGMP.

Pharmacokinetics

Half-life: Fentanyl — 2-4 hours; Sildenafil — 4 hours.

Chemical Properties

Molecular Formula: Fentanyl — C22H28N2O; Sildenafil — C22H30N6O4S.

Molecular Weight: Fentanyl — 336.4700 g/mol; Sildenafil — 474.5800 g/mol.

Type: Fentanyl — Small molecule; Sildenafil — Small molecule.