Finasteride vs Spironolactone

Finasteride vs Spironolactone: Overview

This comparison examines the pharmacological differences between Finasteride and Spironolactone.

Mechanism of Action

Finasteride: Competitive inhibitor of 5-alpha-reductase type II.

Spironolactone: Mineralocorticoid receptor antagonist.

Pharmacokinetics

Half-life: Finasteride — 5-6 hours; Spironolactone — 1.4 hours.

Chemical Properties

Molecular Formula: Finasteride — C23H36N2O2; Spironolactone — C24H32O4S.

Molecular Weight: Finasteride — 372.5490 g/mol; Spironolactone — 416.5740 g/mol.

Type: Finasteride — Small molecule; Spironolactone — Small molecule.