Furosemide vs Spironolactone

## Furosemide vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Furosemide** and **Spironolactone**.

## Mechanism of Action

**Furosemide**: Loop diuretic inhibiting Na-K-2Cl cotransporter.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Furosemide — 2 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Furosemide — C12H11ClN2O5S; Spironolactone — C24H32O4S.

**Molecular Weight**: Furosemide — 330.7440 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Furosemide — Small molecule; Spironolactone — Small molecule.