Gabapentin vs Tramadol

Gabapentin vs Tramadol: Overview

This comparison examines the pharmacological differences between Gabapentin and Tramadol.

Mechanism of Action

Gabapentin: Binds alpha-2-delta subunit of voltage-gated calcium channels.

Tramadol: Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

Pharmacokinetics

Half-life: Gabapentin — 5-7 hours; Tramadol — 5-7 hours.

Chemical Properties

Molecular Formula: Gabapentin — C9H17NO2; Tramadol — C16H25NO2.

Molecular Weight: Gabapentin — 171.2370 g/mol; Tramadol — 263.3750 g/mol.

Type: Gabapentin — Small molecule; Tramadol — Small molecule.