Gefitinib vs Sitagliptin

## Gefitinib vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Gefitinib** and **Sitagliptin**.

## Mechanism of Action

**Gefitinib**: Selective reversible inhibitor of EGFR tyrosine kinase.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Gefitinib — 48 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Gefitinib — C22H24ClFN4O3; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Gefitinib — 446.9000 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Gefitinib — Small molecule; Sitagliptin — Small molecule.