Hydrochlorothiazide vs Naproxen

Hydrochlorothiazide vs Naproxen: Overview

This comparison examines the pharmacological differences between Hydrochlorothiazide and Naproxen.

Mechanism of Action

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Naproxen: Non-selective COX inhibitor.

Pharmacokinetics

Half-life: Hydrochlorothiazide — 6-15 hours; Naproxen — 12-17 hours.

Chemical Properties

Molecular Formula: Hydrochlorothiazide — C7H8ClN3O4S2; Naproxen — C14H14O3.

Molecular Weight: Hydrochlorothiazide — 297.7400 g/mol; Naproxen — 230.2590 g/mol.

Type: Hydrochlorothiazide — Small molecule; Naproxen — Small molecule.