Hydrochlorothiazide vs Norfloxacin

Hydrochlorothiazide vs Norfloxacin: Overview

This comparison examines the pharmacological differences between Hydrochlorothiazide and Norfloxacin.

Mechanism of Action

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Norfloxacin: Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

Pharmacokinetics

Half-life: Hydrochlorothiazide — 6-15 hours; Norfloxacin — 3-4 hours.

Chemical Properties

Molecular Formula: Hydrochlorothiazide — C7H8ClN3O4S2; Norfloxacin — C16H18FN3O3.

Molecular Weight: Hydrochlorothiazide — 297.7400 g/mol; Norfloxacin — 319.3310 g/mol.

Type: Hydrochlorothiazide — Small molecule; Norfloxacin — Small molecule.